jli@ojlab.ac.cn
2007-2012 University of Cologne, Germany Ph.D.
2003-2006 Tianjin University, P.R. China M.S.
1999-2003 Tianjin University, P.R. China B.E.
2023.8-present PI, Facility head Oujiang laboratory, China
2019.8-2023.8 PI, Facility head Gulbenkian Institute, Portugal
2018.6–2019.8 Senior bioinformatician EMBL-EBI, UK
2015.4–2018.2 Senior bioinformatician Sanger Institute, UK
2013.3-2015.3 Postdoc. Max Planck Institute, Germany
Dr. Jingtao Lilue has worked extensively on genomics, immune genetics, and assembly algorithm of new generation sequencing data. In the last 15 years, he has finished the reference genome of more than 20 mammalian species/strains, and reported the mechanism of anti-viral Aim-like receptors in mice, and skin regeneration regulation of Acomys spp. with in silico methods.
At the moment, Lilue group is leading the international rodent genomes project (RD2K, https://rodent2k.org/), and the thousand wild mouse genomes project (WM1000, https://www.wildmousegenomes.com)
Major research interest:
1. Assembly algorithm and quality control of T2T level reference genomes
2. Host-pathogen coevolution in molecular level;
3. AI-based genotype-phenotype correlation of non-model rodent species.
2012 AAI Young Investigator award by American Association of Immunologists
2013 Elsevier Investigator Awards (best overall presentation) by Elsevier
2014 Best scientific publication award by Cologne graduate school (CGS)
Bailey Francis, Landen Gozashti, Kevin Costello, Takaoki Kasahara, Olivia S Harringmeyer, Jingtao Lilue, Mohab Helmy, Tadafumi Kato, Anne Czechanski, Michael A Quail, Iraad Bonner, Emma Dawson, Anne Ferguson-Smith, Laura Reinholdt, David J Adams, Thomas M Keane, The structural diversity of telomeres and centromeres across mouse subspecies revealed by complete assemblies, Nature Genetics, in press, 2025
Mohab Helmy, Jin U Li, Xinyu F Yan, Rachel K Meade, Elizabeth Anderson, Patrick Chen, Anne M Czechanski, Tomás Di Domenico, Jonathan Flint, Erik Garrison, Marco TP Gontijo, Andrea Guarracino, Leanne Haggerty, Edith Heard, Kerstin Howe, Narendra Meena, Fergal J Martin, Eric Miska, Isabell Rall, Navin B Ramakrishna, Alexandra Sapetschnig, Swati Sinha, Diandian Sun, Francesca F Tricomi, Runjia Qu, Jonathan MD Wood, Tianzhen Wu, Dian J Zhou, Laura Reinholdt, David J Adams, Clare M Smith*, Jingtao Lilue*, Thomas M Kean*, The mouse pangenome reveals the structural complexity of the murine protein-coding landscape, Cell Genomics, in press, 2025
Susana Ramos, Temitope W Ademolue, Elisa Jentho, Qian Wu, Joel Guerra, Rui Martins, Gil Pires, Sebastian Weis, Ana Rita Carlos, Ines Mahu, Elsa Seixas, Denise Duarte, Fabienne Rajas, Silvia Cardoso, Antonio GG Sousa, Jingtao Lilue, Tiago Paixao, Gilles Mithieux, Fatima Nogueira, Miguel P Soares, A hypometabolic defense strategy against malaria, Cell metabolism 34, 2022
Jingtao Lilue, Anthony G Doran, ..., Benedict Paten, Thomas M Keane, Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci, Nature Genetics 50, 2018
Ricardo T Gazzinelli, Rondon Mendonça-Neto, Jingtao Lilue, Jonathan Howard, Alan Sher, Innate resistance against Toxoplasma gondii: an evolutionary tale of mice, cats, and men, Cell host & microbe 15, 2014
