yangliuqing@ojlab.ac.cn
September 2001-June 2005
Bachelor of Science, Wuhan University, China
Major: Biotechnology
September 2006-June 2008
Master of Science, Wuhan University, China
Major: Biochemistry and Molecular Biology
August 2009-May 2015
Doctor of Philosophy, University of Kentucky, USA
Major: Biochemistry
May 2015-May 2021
Postdoctoral fellow, Johns Hopkins University Department of Neuroscience, Paul Worley lab
May 2021-March 2023
Research associate, Johns Hopkins University Department of Neuroscience
April 2023-present
Principal investigator, Oujiang Laboratory, Wenzhou, China
Episodic memory comprises experiences containing spatial-temporal information (where, when and what) that can be consciously recalled. Episodic memory is stored in (or via) entorhinal-hippocampal circuit, the navigation system in mammalian brain (place cells and grid cells). Episodic memory decline is the earliest and most prominent symptom of Alzheimer’s disease (AD), the most prevalent neurodegenerative disease. Our lab studies episodic memory encoding, storage and retrieval using viral tools that make memory-encoding neurons (engram neurons) visible in the hippocampus. We also study the mechanism of episodic memory decline in AD and develop nucleic acid-based novel interventive approaches for neurodegenerative diseases including AD and amyotrophic lateral sclerosis (ALS).
2015
Max Steckler Award, University of Kentucky Graduate School, USA
2018
NARSAD Young Investigator Award, Brain & Behavior Research Foundation, USA
2023
Zhejiang province oversea talents recruiting program, Zhejiang, China
Grants
2019-2022
NARSAD Young Investigator Grant (27824), Brain & Behavior Research Foundation, USA
2023-2028
Oujiang Laboratory starting grant OJQD2023001
2024-2027
Wenzhou Science and Technology Project (2024R2002)
Liuqing Yang, Wenxue Liu, Linyuan Shi, Jing Wu, Wenchi Zhang, Yang-An Chuang, Javier Redding-Ochoa, Alfredo Kirkwood, Alena V. Savonenko, and Paul F. Worley. (2023) NMDAR-Arc signaling is required for Memory Updating and is disrupted in Alzheimer’s Disease. Biological Psychiatry. DOI: 10.1016/j.biopsych.2023.02.008
Wenchi Zhang, Yang-An Chuang, Youn Na, Zengyou Ye, Liuqing Yang, Raozhou Lin, Jiechao Zhou, Jing Wu, Jessica Qiu, Alena Savonenko, Daniel J. Leahy Richard Huganir David J. Linden, Paul F. Worley. (2019) Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation. Molecular Cell. 75, 13–25.
Liuqing Yang, Jiayu Zhang, Marisa Kamelgarn, Chunyan Niu, Jozsef Gal, Weimin Gong, Haining Zhu. (2015) Subcellular localization and RNAs determine FUS architecture in different cellular compartments. Human Molecular Genetics. 24(18): 5174-83.
