liuminggang@ojlab.ac.cn
2005.09-2010.07 Capital Medical University, Beijing, China
2000.09-2005.07 Binzhou Medical College, Binzhou, Shandong, China
2023.12-now Principal investigator, Oujiang laboratory, Wenzhou, China
2020.01-2023.11 Research Fellow at Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
2015.01-2019.12 Associate Researcher at Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
2014.04-2014.12 Assistant researcher at Department of Anatomy and Embryology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
2013.02-2014.03 Postdoc fellow at Department of Physiology, University of Toronto, Toronto, Canada
2011.06-2013.01 Postdoc fellow at Department of Brain and Cognitive Sciences, Seoul National University, Seoul, Korea
2010.09-2011.06 Postdoc fellow at Department of Physiology, Nihon University School of Dentistry, Chiyoda-ku, Tokyo, Japan
In the past several years, my research interest mainly focuses on neurobiological mechanisms of pain and itch. Employing multi-level cutting-edge techniques in neuroscience, we sought to dissect the neuronal, synaptic, and circuit mechanisms involved in the processing, encoding, and regulation of pain and itch signals, as well as the pathogenesis of chronic pain/itch and their comorbidities. Furthermore, another research interest of the team is to systematically investigate the neural mechanisms underlying the generation, development, regulation, and dysfunction of higher cognitive functions such as empathy, and to develop novel therapeutic strategies for treating empathy-related neurological disorders. To date, I have published more than 40 papers in SCI-included international journals, such as Neuron, Science Advances, Nature Communications, Cell Reports, Journal of Neuroscience and etc. Specifically, my research interest include:
1. Neural mechanisms of somatosensation and its disorders;
2. Neural mechanisms underlying the interactions between sensation and emotion;
3. Neural basis for the generation and regulation of empathic behaviors and associated dysfunctions.
1. Second Prize of Medical Science and Technology Award of Chinese Medical Association, 2020.
2. Young Scientist Award for Neuroscience in the Yangtze River Delta, 2019.
3. Award for outstanding young teachers at Shanghai Jiaotong University School of Medicine, 2017-2020.
4. Award for Shanghai Young Oriental Scholar, 2015-2017.
5. Award for Excellent Oral Presentation at The Second Annual Scientific Meeting of Department of Neurobiology, Capital Medical University, 2010.
6. Award for Outstanding Postgraduate Student in Capital Medical University, 2009.
(1) Zhang Z*, Gong Y*, Su XY, Deng Y, Du R, Li CL, Wang Y, Song XL, Jiang Q, Li Y, Jian Y, Tong X, Wang GH, Chen J, Xu TL#, Liu MG#, Jiang F#. Dysfunction of the paraventricular thalamus-prelimbic cortex circuit underlies maternal separation-induced deficits in contagious pain. Sci Adv (in press)
(2) Guo SS*, Gong Y*, Zhang TT*, Su XY, Wu YJ, Yan YX, Cao Y, Song XL, Xie JC, Wu D, Jiang Q, Li Y, Zhao X, Zhu MX#, Xu TL#, Liu MG#. A thalamic nucleus reuniens-1 lateral septum-lateral hypothalamus circuit for comorbid anxiety-like behaviors in chronic itch. Sci Adv 2024, 10:eadn6272.
(3) Pan Q*, Guo SS*, Chen M*, Su XY, Gao ZL, Wang Q, Xu TL#, Liu MG#, Hu J#. Representation and control of pain and itch by distinct prefrontal neural ensembles. Neuron 2023, 111:2414-2431.
(4) Wang YJ*, Liu MG*, Wang JH*, Cao W*, Wu C, Wang ZY, Liu L, Yang F, Feng ZH, Sun L, Zhang F, Shen Y, Zhou YD, Zhuo M, Luo JH#, Xu TL#, Li XY#. Restoration of cingulate long-term depression by enhancing non-apoptotic caspase 3 alleviates peripheral hypersensitivity. Cell Rep 2020, 33:108369.
(5) Su XY*, Chen M*, Yuan Y, Li Y, Guo SS, Luo HQ, Huang C, Sun W, Li Y, Zhu MX, Liu MG#, Hu J#, Xu TL#. Central processing of itch in the midbrain reward center. Neuron 2019, 102:858-872.
(6) Li WG*, Liu MG*, Deng S*, Liu YM, Shang L, Ding J, Hsu TT, Jiang Q, Li Y, Li F#, Zhu MX#, Xu TL#. ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion. Nat Commun 2016,7:13770.
(7) Li WG*, Liu MG*, Deng S*, Liu YM, Shang L, Ding J, Hsu TT, Jiang Q, Li Y, Li F#, Zhu MX#, Xu TL#. ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion. Nat Commun 2016,7:13770.
