xfxj2000@126.com
1998-2003 B.S. Jiangxi Medical University
2003-2006 M.S. Jinan University
2007-2010 Ph.D. Sun Yat-Sen University
2006-2010 Assistant Professor, School of Pharmaceutical Sciences, Wenzhou Medical University
2009-2010 Visiting Scholar, School of Medicine, Virginia Commonwealth University
2011-2014 Associate Professor, School of Pharmaceutical Sciences, Wenzhou Medical University
2014-Present Professor, School of Pharmaceutical Sciences, Wenzhou Medical University
Dr. Jian Xiao has committed himself to scientific research and applied Research for 20 years in wound repair. Based on the background of skin wound healing and nerve injury repair by growth factors, he launched a series of research and published 100 papers. He also got 41 patents of invention, 1 new drug license and 3 medical device license. His major achievements are: 1, discovered that the mechanisms of fibroblast growth factor (FGF) in skin wound healing are acceleration of wound closure, inhibition of scar formation, decrease pigmentation, and promotion of hair growth, demonstrated that FGF stimulate skin functional repair. His studies also proved that FGFs exert the bioactivity including neuronal protection, axon regeneration, and inhibition of glial scarring.repair of spinal cord injury, which contribute to the functional recovery of spinal cord injury (SCI). 2, developed several biomaterials which can improve the release and efficacy of FGFs to treat skin wound and SCI, proposed a new theory for design the biomaterials to encapsulate growth factors. In particular, he won the first class National Award of Science and Technology (2015), the second class National Award of Science and Technology (2018).
The First Class National Award of Science and Technology in 2015.
The Second Class National Award of Science and Technology in 2018
1. Fan Zhang, Haijuan Zhang, Shengfu Wang, Mingying Gao*, Kaiyi Du, Xinyuan Chen, Yang Lu, Qianqian Hu, Anyu Du, Shenghu Du, Jian Wang, Keqing Shi, Zimiao Chen, Zhuo Li*, Zhenglin Li*, Jian Xiao*. A dynamically phase-adaptive regulating hydrogel promotes ultrafast anti-fibrotic wound healing. Nat Commun, 2025 Apr 20；16(1):3738. (IF 15.7)
2. Mi Liu, Huiming Deng, Chunyan Liu, Lintao Wang, Zhongkai Liao, Desheng Li, Yan Chen, Chunming Wang*, Ling Huang*, Lei Dong*, Jian Xiao*. Islet Transplantation in Biomaterials-remodeled Spleens. Sci Transl Med, 2025 May 21；17(799):eadj9615. (IF 14.6)
3. Chen Jin, Du-piao Zhang, Yu-zhe Lin, Zhen Lin, Yi-feng Shi, Xiao-yu Dong, Meng-qi Jin, Fuqiang Song, Siting Du, Yanzhen Feng, Linyuan Jiang, Xiao-qiong Jiang, Zi-li He, Zimiao Chen, Jian Wang, Keqing Shi, Zhenglin Li*, Lei Yang*, Jian Xiao*. Piezo1 channel inhibition targets ferroptosis promote wound healing in aging mice. Research, 2025, 2025:0718. (IF 10.7)
4. Chen Jin, Li-jiang Han, Ri-yan Zhang, Du-piao Zhang, Le-yang Liu, Kai-kai Xue, Jie Xu, Yu-zhe Lin, Yi-feng Shi, Meng-qi Jin, Jian-sen Miu, Ying-feng Lu, Le-yi Cai, Zhen Lin, Lei Yang, Jian Xiao*. A multifunctional hydrogel promotes diabetic wound healing by remodeling iron metabolism and energy metabolism. Biomaterials. 2025, 326:123640. (IF 12.9)
5. Anqi Ye, Hao Mei, Zheng Zhang, Fuqiang Song, Linyuan Jiang, Ting Huang, Ping Li, Siting Du, Yanzhen Feng, Tianyao Jiang, Fenzan Wu, Li Cheng, Jia Qu*, Jian Xiao*. Corneal First Aid Lens: Multifunctional Atelocollagen Corneal Contact Lens Designed for the Treatment of Corneal Injuries and Dry Eyes. J Control Release, 2025 Jan 13:379:251-265. (IF 11.5，封底论文)
6. Qingwei Zhou, Junjie Chi, Jintao Yang, Jiali Guo, Feifei Lian, Abdullah Al Mamun, Tianling Chen, Haijuan Zhang, Jiaojiao Chen, Yibing Tao, Keqing Shi*, Jian Xiao*. Natural, Safety Immunomodulatory Derivatives of Lactobacillus Biofilms Promote Diabetic Wound Healing by Metabolically Regulating Macrophage Phenotype and Alleviating Local Inflammation. J Adv Res, 2025 Apr 3:S2090-1232(25)00220-6. (IF 13)
7. Xiaoqiong Jiang, Xuanlong Zhang, Huiming Deng, Lulu Lin, Yu Wang, Gaoxiang Yu, Ningning Yang, Shi Xu, Jian Wang, Keqing Shi, Ke Tao, Zimiao Chen, Fuman Cai*, Kailiang Zhou*, Jian Xiao*. Modulation of Macrophage Ferroptosis under the Guide of Infrared Thermography Promotes the Healing of Pressure Injuries. J Adv Res, 2025 Apr 26:S2090-1232(25)00283-8. (IF 13)
8. Siting Du, Yueting Li, Yanzhen Feng, Quan Zhou, Jianfeng Wang, Imran Ibrahim Shaikh, Fuqiang Song, Ayesha Younas, Shuanghu Wang, Jian Xiao*. Multifunctional photothermal-driven PEG-Grafted/CuS-Loaded Dendritic Mesoporous Organosilicon nanomotors for accelerated wound healing. Chem Eng J. 2025, 520: 165816. (IF 13.4)
