fye@iphy.ac.cn
2002-2007 University of Pennsylvania DD
2000-2002 University of Pennsylvania MD
1995-1999 Peking University BD
2019.5-present Associate Dean Wenzhou Research Institute of University of Chinese Academy of Sciences
2017.9 -present Deputy Director of the Laboratory Soft Matter Laboratory, Institute of Physics, Chinese Academy of Sciences
2013.05-present Researcher Institute of Physics, Chinese Academy of Sciences
2011.8-2013.4 Postdoctoral Georgia Institute of Technology
2009.2-2011.8 Postdoctoral University of Illinois at Urbana-Champaign
2007.7-2009.2 Postdoctoral Kent State University
Prof. Fangfu Ye and his team have been dedicated to answering key questions in the field of soft matter physics and statistical physics. His major research field is soft condensed matter physics, biophysics, and biomedical engineering. He has conducted innovative work in the active matter, cell dynamics modeling and behavior prediction, as well as the construction and application of intelligent micro/nanostructured biomaterials. By integrating soft matter physics with cutting-edge biomedical technologies, the research bridges the design of functional biomaterials guided by soft matter physics with their ultimate application in medical practice.
His research interest include:
1. Regulation of extracellular microenvironment on the behavior of nerve cells, tumor cells, stem cells, etc.;
2. Study of interactions between cell membranes and proteins;
3. Design of functional biomaterials;
4. Development of medical imaging and detection technologies;
5. Structural properties and phase transitions of complex networks;
6. Collective behavior of self-spinning particle systems.
2024 NSFC Distinguished Young Scholar Fund
2024 Second Prize, 13th China Innovation & Entrepreneurship Competition - Innovation Challenge (Zhejiang) & 2024 Zhejiang Province "Unveiling the List and Bestowing the Command" Technology Demand Matching Contest
2023 First Prize, Chinese Chemical Society Award for Research on Mass Transfer Intensification in Microfluidics and the Control Mechanism of Particle Morphology
1. Chenjing Yang, Baiheng Wu, Jian Ruan, Peng Zhao, Li Chen, Dong Chen*, and Fangfu Ye*. 3D-Printed Biomimetic Systems with Synergetic Color and Shape Responses Based on Oblate Cholesteric Liquid. Adv. Mater. 2021, 33(10), 2006361.
2. Qihui Fan, Yu Zheng, Xiaochen Wang, Ruipei Xie, Yu Ding, Boyi Wang, Xiaoyu Yu, Ying Lu, Liyu Liu, Yunliang Li, Ming Li, Yuanjin Zhao*, Yang Jiao*, and Fangfu Ye*. Dynamically Re-Organized Collagen Fiber Bundles Transmit Mechanical Signals and Induce Strongly Correlated Cell Migration and Self-Organization. Angew. Chem. Int. Ed. 2021, 60(21), 11858-11867.
3. Wenwen Diao, Jing Peng, Xiaodi Fu, Fangfu Ye*, Zhanfeng Wang*. Preorganized Internal Electric Field Enables Nucleophilic Attack of a Nonactivated Water Molecule in Thymine DNA Glycosylase. J. Am. Chem. Soc. 2025, 147, 29, 25919–25930.
4. Lexiang Zhang, Dexuan Wang, Fangfu Ye*, Min Wu*. Macrophage-dormant disseminated cancer cell interactions: valuable implications for metastasis and prevention. Sci. Bull. 2025, 70, 1899-901.
5. Xiaochen Wang, Hangyu Li, Yu Zheng, Dongshi Guan, Aidan Wang, Qihui Fan*, Yang Jiao*, Fangfu Ye*. Collective Organization Behaviors of Multi-Cell Systems Induced by Engineered ECM-Cell Mechanical Coupling. Adv. Funct. Mater. 2023, 33, 2305414.
6. Changmin Shao, Junjie Chi, Zhuoyue Chen, Lingyu Sun, Luoran Shang*, Yuanji Zhao*, Fangfu Ye*. Nano-imprinted anisotropic structural color graphene films for cardiomyocytes dynamic displaying. Mater. Today 2021, 51, 117-125.
