srw@ojlab.ac.cn
1993-1996 University of Wales, UK | Ph.D. in Physiology
1992-1993 University of Oxford, UK | M.Sc. in Neuropharmacology
1989-1992 University of Wales, UK | B.Sc. in Physiology
2024–Present Senior Investigator Oujiang Laboratory
2024–2025 Professor Monash University, Australia
2014–2023 Professor The University of Queensland, Australia
2010–2014 Associate Professor The University of Queensland, Australia
2008–2009 Tenured Project Leader Neurobiology Division, MRC Laboratory of Molecular Biology, UK
2002–2008 Project Leader Neurobiology Division, MRC Laboratory of Molecular Biology, UK
2001–2002 Research Fellow The John Curtin School of Medical Research, The Australian National University, Australia
1997–2000 Postdoctoral Fellow The John Curtin School of Medical Research, The Australian National University, Australia
1996–1997 Postdoctoral Fellow Epilepsy Foundation of America / University of California, Los Angeles (UCLA), USA
1. Molecular, biophysical, and structural characterization of identified neuronal classes in the neocortex of humans and non-human primates. Investigation of the enhanced information processing capabilities of human and non-human primate neocortical neurons and circuits.
2. Functional and structural deconstruction of neuronal circuit activity underlying sensory and cognitive behavior. Exploration of region-specific neuronal and network computations in the human neocortex.
3. Elucidation of neocortical computational mechanisms critical to human cognition and mental health. Design and implementation of biophysically inspired artificial neural networks.
2024 Kunpeng Plan Recipient
2019 National Health and Medical Research Council Investigator Scientist (Australia)
2015 Paxinos–Watson Prize (Australian Neuroscience Society)
2011 Australian Research Council Future Fellow
2008 Paxinos–Watson Prize (Australian Neuroscience Society)
2004 Max Perutz Open Prize (Medical Research Council, UK)
1995 Pfizer Prize (The Physiological Society, UK)
WILLIAMS, S.R., ZHOU, X., & FLETCHER, L.N. (2023). Compartment-specific dendritic information processing is reconfigured by peptide neuromodulation in striatal cholinergic interneurons. Neuron, 111, 1933-195.
BROMBAS, A. ZHOU, X. & WILLIAMS, S.R. (2022). Light-evoked dendritic spikes in sustained but not transient rabbit retinal ganglion cells. Neuron, 110, 2802-2814.
GOOCH, H.M., BLUETT, T., PERUMAL, M.B., VO, H.D., FLETCHER, L.N., PAPACOSTAS, J., JEFFREE, R.L., WOOD, M., COLDITZ, M.J., MCMILLEN, J., TSAHTSARLIS, T., AMATO, D., CAMPBELL, R., GILLINDER, L., & WILLIAMS, S.R. (2022). High-fidelity dendritic sodium spike generation in human layer 2/3 neocortical pyramidal neurons. Cell Reports, 41(3):111500.
WILLIAMS, S.R. & FLETCHER, L.N. (2019). A dendritic substrate for the cholinergic control of neocortical output neurons. Neuron, 101, 486-499.
FLETCHER, L.N. & WILLIAMS, S.R. (2019). Neocortical topology governs the dendritic integrative capacity of layer 5 pyramidal neurons. Neuron, 101, 76-90.
BROMBAS, A.* , KALITA-de CROFT, S.* , COOPER-WILLIAMS, E.J. & WILLIAMS, S.R. (2017). Dendro[1]dendritic cholinergic excitation controls dendritic spike initiation in retinal ganglion cells. Nature Communications, 7, 8:15683
SIVYER, B. & WILLIAMS, S.R. (2013). Direction selectivity is computed by active dendritic integration in retinal ganglion cells. Nature Neuroscience, 16, 1848-1856. 15.
HARNETT, M.T., XU, N-L, MAGEE, J.C. & WILLIAMS, S.R. (2013). Potassium channels control the interaction between active dendritic integration compartments in layer 5 cortical pyramidal neurons. Neuron, 79, 516-529. 16.
